SeaChem Cupramine is superior to copper sulfate, chloride & citrate: it is non-acidic, less toxic to fish, remains in solution, and does not contaminate the filter bed. Seachem Cupramine is superior to traditional chelates: it is fully charged (ionic), active at low concentrations, and is can be removed from your water with carbon.

Buffered active copper
For marine or freshwater
Less toxic, superior to & safer than copper chlorides, sulfates, citrates & chelates